A micro-needle patch (MAP) is an innovative method to deliver drugs and vaccines. Credit: QuadMedicine
A micro-needle patch (MAP) is an progressive methodology to ship medication and vaccines. Credit score: QuadMedicine
  • by Busani Bafana (seoul)
  • Inter Press Service

A South Korean firm’s invention of an progressive micro-needle patch may make you stay up for your subsequent physician’s go to.

The micro-needle patch (MAP) is a painless, cost-effective, and environmentally pleasant approach to administer vaccines and medicines rather than strong injections, its builders say.

The MAP system has the mixed benefits of standard patches and syringes. It has tiny needles whose suggestions are much less invasive and virtually painless when administering medication, Chi Yong Kim, Analysis Coordinator at QuadMedicine, tells IPS.

“The sensation of the micro-needle is sort of a cat’s tongue. It is like a scratch that doesn’t trigger ache,” Kim says of the MAP, which additionally delivers energetic pharmaceutical elements (APIs) within the right quantities.

QuadMedicine has patented the type of micro-needle patches which can be separable MAPs, the place the information of the needle themselves are energetic APIs. In delivering the API, the information of the micro-needle are inserted into the pores and skin and break off, lowering supply time and rising supply effectivity by virtually 100%, mentioned Kim.

Kim notes that the MAPS additionally supply the benefit of portability, and they’re secure at room temperature, making them straightforward to hold, retailer, and transport earlier than they’re administered. Moreover, the MAP could be recycled safely with out producing a lot waste.

In accordance with the World Well being Group, yearly, an estimated 16 billion injections are administered worldwide, however not the entire needles and syringes are correctly disposed of, making it essential to make sure protected and environmentally sound administration of well being care waste.

“Alternatively, we will additionally freeze dry types of vaccines that use the identical powder type of API,” he mentioned, including that lyophilized powder could be connected to the MAP.

The corporate is now investigating comparable vaccines and medicines, as an example, the messenger mRNA vaccines that can be utilized within the microneedle or patch platform. Plans are afoot to submit an IND submitting for a scientific trial quickly, and prototypes of the coated MAP and the separable MAP will likely be examined by Part I to III scientific trials.

Kim mentioned low- and middle-income international locations in addition to the premium market have been focused for innovation, which implies vaccine-loaded MAPs will likely be reasonably priced for international well being.  For instance, sure vaccines, such because the influenza vaccine, have a dosage-saving impact when utilized with a micro-needle. The identical quantity of antigen used for the intramuscular route with a syringe is not used, so the API quantity could be diminished when loaded on the micro-needles.

Whereas professionals like medical employees or docs should at present inject vaccines, the aim with the micro needles or patches is that volunteers can provide them to sufferers who want vaccinations.

“I’ve a concern of the sharps,” Kim mentioned, explaining that every time he visited the hospital, nurses requested him to chill out in order that his muscle tissues couldn’t be punched.

“I took my youngsters to the household physician, and there was one possibility, the strong micro needle,” he mentioned, explaining {that a} private expertise with the concern of needles was a coincidental determination for him to specialize at QuadMedicine, which has been concerned within the growth of the MAPS and patches.

“We have now been creating new platforms to ship vaccines and medicines by coated MAP or dissolvable MAP, which is a potential different to strong needles and a greater resolution to ship the right amount of the medication and vaccines for our physique to make good immune responses.”

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